Kitty Flipping: Ketamine and MDMA Stimulant Combinations
The latest news of deaths from club drug combinations in Miami

By Mark S Gold
Published by Psychology Today on September 21, 2025

Key points

“Kitty flipping” is mixing the dissociative anesthetic ketamine and stimulant/empathogen MDMA.
Increasing numbers of ketamine-related deaths, often with MDMA, are reported in Miami and other major cities.
Ketamine is given safely when administered and supervised in the hospital, clinic or office by physicians.

“Kitty flipping”, the practice of combining MDMA (ecstasy) and ketamine, is often confused with the term “candy flipping,” in which MDMA is combined with LSD. Historically, kitty flipping refers to the use of MDMA and ketamine within the same short time period, but new drug seizure data suggest that MDMA and ketamine are also pre-mixed and sold for “kitty flipping”.

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